Nyob rau hauv xyoo tas los no, nrog kev siv cov khoom yas dav dav, microplastics tau dhau los ua thoob plaws hauv ib puag ncig. Qhov tseem ceeb tshaj, kev tshawb fawb ntxiv qhia tau hais tias cov microplastics tuaj yeem sau rau hauv tib neeg lub cev; Cov kws tshawb fawb tau pom lawv hauv cov ntshav, lub ntsws, lub raum, lub siab, lub cev xeeb tub, thiab txawm tias lub hlwb.
Hauv lub neej tiag tiag, microplastics nyob txhua qhov chaw. Cov huab cua peb ua pa, dej hauv lub raj mis, lub hnab ntim khoom noj, cov thawv ntim khoom noj, thiab lwm yam, ua rau peb raug thiab noj cov microplastics, uas tuaj yeem ua rau ntau yam kabmob thiab lub cev hauv tib neeg lub cev. Cov kev tshawb fawb yav dhau los tau tsom mus rau kev kuaj pom muaj cov microplastics, qhia txog lawv qhov muaj peev xwm ua rau muaj kev phom sij, thiab tshem tawm cov microplastics ntawm ib puag ncig. Rau microplastics uas twb tau ua phem rau tib neeg lub cev, tseem tsis muaj lub tswv yim zoo rau kev tshem tawm.
Tsis ntev los no, ob txoj kev tshawb fawb tshiab los ntawm cov kws tshawb fawb Suav tau coj qhov kev hloov pauv tshiab hauv kev tshem tawm microplastic- siv cov probiotics uas tau tshawb pom tshiab los adsorb thiab txhawb kev tshem tawm cov microplastics ntawm lub cev, thaum tib lub sijhawm kho cov kev puas tsuaj los ntawm microplastics.
Thaum Lub Ib Hlis 10, 2025, ib pab neeg tshawb fawb coj los ntawm Dr. Rao Chitong, Tus Thawj Saib Xyuas Kev Tshawb Fawb ntawm Blue Crystal Microbiology, tau luam tawm cov ntaub ntawv tshawb fawb hu ua "Novel probiotics adsorbing thiab excreting microplastics in vivo show can be gut health benefits" nyob rau hauv phau ntawv Journal Frontiers in Microbiology.
Cov pa phem microplastic los ntawm cov zaub mov thiab dej ua rau muaj kev pheej hmoo loj rau kev noj qab haus huv. Cov kab mob muaj peev xwm tshem tawm cov microplastics ntawm ib puag ncig, tab sis tam sim no tsis muaj txoj hauv kev los tshem tawm cov uas tsis yog -degradable microplastics twb muaj nyob rau hauv tib neeg lub cev. Hauv txoj kev tshawb fawb tshiab no, pab pawg tshawb fawb tau thov kom siv cov tshuaj probiotics rau adsorb thiab tshem tawm cov kab mob microplastic hauv plab.
Pab neeg tshawb fawb tau siv txoj hauv kev zoo -throughput tshuaj ntsuam xyuas 784 kab mob los txiav txim seb lawv muaj peev xwm adsorb 0.1-micron-loj polystyrene (PS, feem ntau siv hauv cov khoom siv, khoom ua si, khoom siv niaj hnub, ntim yas, khoom siv hauv tsev, thiab khoom siv kho mob). Ntawm cov kab mob no, pab pawg tshawb fawb tau tshawb pom tias ob lub probiotics-Lactobacillus paracasei DT66 thiab Lactobacillus plantarum DT88-tso tawm qhov zoo tshaj plaws microplastic particle adsorption nyhuv hauv vivo, thiab tau zoo tiv thaiv ntau hom microplastics (PS, PE, PC, PP, thiab PET).
Scanning electron microscopy pom tias probiotics DT66 thiab DT88 tuaj yeem nqus cov microplastics
Tom ntej no, pab neeg tshawb fawb tau ua hauv vivo tsiaj sim. Tom qab cov nas tau noj cov tshuaj probiotics hauv qhov ncauj, cov probiotics muaj peev xwm adsorb microplastics zoo li cov hlau nplaum, tsim "cov kab mob-plastic clumps," uas tom qab ntawd tawm hauv lub cev. Tshwj xeeb, qhov tso tawm ntawm microplastics nyob rau hauv lub plab zom mov ntawm nas nce los ntawm 36%, thiab tus nqi ntawm cov seem microplastic nyob rau hauv cov hnyuv txo los ntawm 67%.
Tsis tas li ntawd, txoj kev tshawb no kuj tau lees paub tias Lactobacillus plantarum DT88 strain tuaj yeem txo cov hnyuv mob los ntawm polystyrene (PS) microplastics. Hauv cov ntsiab lus, txoj kev tshawb no nthuav tawm cov tswv yim tshiab probiotic rau kev hais txog microplastic- cuam tshuam txog kev noj qab haus huv, qhia txog lub peev xwm ntawm kev siv cov kab mob tshwj xeeb ntawm probiotics los tshem tawm cov microplastics ntawm lub plab ib puag ncig thiab txo cov kev pheej hmoo no.
Probiotics DT66 thiab DT88 txhawb nqa microplastic tshem tawm
Thaum Lub Ob Hlis 1, 2025, pab pawg coj los ntawm Rao Chitong los ntawm Lanjing Microbiology, koom tes nrog pab pawg coj los ntawm Wang Gang los ntawm Jiangnan University, tau tshaj tawm cov ntawv tshawb fawb hauv phau ntawv journal *Environmental Pollution* muaj cai: "Lactic acid bacteria txo polystyrene micro- thiab nanoplastics-induced muaj peev xwm los ntawm bioplastics muaj peev xwm."
Microplastics yog ib qho kev ua paug ib puag ncig tshiab uas tau txais kev saib xyuas ntau hauv xyoo tas los no. Tam sim no, muaj kev tshawb fawb txog cov tshuaj lom ntawm microplastics ntawm cov tsiaj (tshwj xeeb yog cov kab mob hauv dej thiab cov tsiaj nyeg), tab sis kev tshawb fawb thiab cov ntaub ntawv ntawm kev txo cov tshuaj lom ntawm cov khoom raug txwv.
Cov kab mob lactic acid (LAB, suav nrog Lactobacillus) tau lees paub tias yog zaub mov zoo- qib probiotics. Lawv muaj lub peev xwm los kho cov kab mob hauv plab hnyuv, tswj cov plab hnyuv microbiota, thiab hloov kho lub cev tiv thaiv kab mob. Lawv kuj muaj peev xwm los biobind cov khoom tsis zoo, muaj peev xwm adsorbing microplastics hauv tib neeg lub cev thiab txo lawv cov qib tsub zuj zuj, yog li txo cov toxicity.
Hauv txoj kev tshawb fawb tshiab no, pab pawg tshawb fawb tau xaiv cov kab mob lactic acid (DT11, DT22, DT33, DT55, thiab DT66) nrog rau qhov sib txawv hauv vitro microplastic binding muaj peev xwm los cuam tshuam cov nas uas raug microplastics, tshawb xyuas lawv cov txiaj ntsig hauv kev txo cov tshuaj lom neeg los ntawm microplastic raug.
Cov txiaj ntsig tau pom tias cov kab mob lactic acid nrog ntau dua microplastic adsorption muaj peev xwm (DT11, DT33, DT55, thiab DT66, nrog adsorption tus nqi siab tshaj 60%) tau zoo dua los txo cov tshuaj lom los ntawm microplastic raug. Txawm li cas los xij, nws yog ib qho tseem ceeb uas * Lactobacillus plantarum * DT22, txawm hais tias muaj qhov tsis tshua muaj microplastic adsorption (kwv yees li 10%), tau ua lub luag haujlwm tseem ceeb hauv kev txhawb nqa cov lus qhia ntawm cov protein ntau nruj (xws li ZO-1) thiab tswj cov plab hnyuv microbiota.
Lactobacillus strains nthuav tawm microplastic adsorption, ob qho tib si hauv vivo thiab hauv vitro, txo cov toxicity (xws li, hepatotoxicity thiab testicular toxicity) tshwm sim los ntawm microplastic raug. Cov nyhuv no yog ua tiav los ntawm ob txoj kev ua tau: ua ntej, lactobacillus tuaj yeem nqus cov microplastics thiab txhawb nqa lawv cov kev tso tawm hauv cov quav, yog li txo lawv cov tsub zuj zuj hauv vivo; Thib ob, lactobacillus tuaj yeem kho cov kab mob hauv plab hnyuv, tswj cov plab hnyuv microbiota, thiab ua kom cov khoom luv luv ntawm -cov saw fatty acids (xws li, butyrate).
Lactobacillus txo microplastic- ua rau lub siab puas tsuaj
Lactobacillus txo microplastic-induced testicular thiab colonic puas
Cov txiaj ntsig no qhia tau hais tias kev txo qis ntawm lactobacillus ntawm microplastic toxicity tsis yog nyob rau hauv nws lub peev xwm biobinding xwb tab sis kuj nyob rau hauv nws lub peev xwm los kho lub plab hnyuv ib puag ncig. Hauv lwm lo lus, lactobacillus tsis yog tsuas yog "carrier" hauv plab (txhawb microplastic excretion) tab sis kuj yog "repairman" (kho microplastic-induced puas). Yog li, pab pawg tshawb fawb pom zoo kom siv cov kab mob probiotic lactic acid los ua kev noj zaub mov kom txo tau cov tshuaj lom los ntawm microplastics. Zuag qhia tag nrho, ob qhov kev tshawb pom tshiab no muab txoj hauv kev tshiab los daws cov teeb meem microplastic thiab qhib txoj hauv kev tshiab rau kev txhim kho plab hnyuv thiab rov ua kom lub plab microbiome tshuav, yog li muaj qhov cuam tshuam rau ib puag ncig thiab kev noj qab haus huv.
